With the increase in the life expectancy of the population, the prevalence of acute and chronic skin wounds that present scarring problems have increased. Surgeries, accidental lacerations, infections, burns, pressure ulcers, venous or diabetic are some of the main causes of this increase in acute wounds, whose treatment involves a high cost.

With the aim of finding new therapeutic approaches for a better and faster healing of this type of wounds, medical researchers have developed an experimental study in which it uses a new regenerative therapy for the skin of wounds: the combination of plasma rich in growth factors and mesenchymal stem cells, coming from the adipose tissue.

The results obtained have improved both the healing time of the skin and the aesthetic appearance of the scar.

Regarding the macroscopic cutaneous cicatrization of the wounds treated with these regenerative therapies, a statistically significant acceleration was observed in those wounds that were infiltrated with mesenchymal stem cells, in isolation or associated with plasma rich in growth factors. These wounds had higher percentages of cutaneous scarring than those treated with this type of plasma alone or with placebo.

Regarding the evaluation of the aesthetic aspect of the wounds, those that receive treatment only with mesenchymal stem cells are those that achieve a scar coloration and thickness more similar to a short-term physiological scar. But, also in this aesthetic aspect, the results are better when the two therapies with cells and plasma are associated.

A strong stimulation of cutaneous epithelization was also observed in a statistically significant way throughout the study times in the wounds that were treated with mesenchymal stem cells, isolated or jointly with plasma rich in growth factors, especially in the short term, in the first five days of observation.